In collaboration with the Flood group, we study supramolecular anion-receptor complexes. Fragment-based methods employed to calculate binding affinites of foldamer-anion complexes
Recent Publications:
"Solvent-Dependent Folding Behavior of a Helix-forming Aryl-Triazole Foldamer”, S. Debnath, A. H. Flood, and K. Raghavachari, J. Phys. Chem. B (2024). https://doi.org/10.1021 /acs.jpcb.3c04907
"Cooperativity in Photofoldamer-Chloride Double Helices Turned On with Sequences and Solvents, Around with Guests, and Off with Light”, A. Lutolli, M. Che, F. C. Parks, K. Raghavachari, A. Flood, J. Org. Chem. 88, 6791−6804 (2023). https://doi.org/10.1021/acs.joc.3c00112
"High-fidelity Recognition of Organotrifluoroborate Anions (R–BF3−) as Designer Guest Molecules”, E. G. Sheetz, Z. Zhang, A. Marogil, M. Che, M. Pink, V. Carta, K. Raghavachari, and A. H. Flood, Chem. Eur. J. 28, e2022015(1-5) (2022), https://doi.org/10.1002/chem.202201584
"Revealing the Hidden Costs of Organization in Host-Guest Chemistry using Chloride-Binding Foldamers and their Solvent Dependence”, F. C. Parks, E. G. Sheetz, S. R. Stutsman, A. Lutolli, S . Debnath, K. Raghavachari, and A. H. Flood, J. Am. Chem. Soc. 144, 1274−1287 (2022) https://doi.org/10.1021/jacs.1c10758
